I use this guide to help pharmaceutical, medicinal chemistry, and advanced organic synthesis buyers evaluate 2,6-Bis(benzyloxy)pyridine-3-boronic acid, identified by CAS 2096339-92-1. This compound is a pyridine-containing boronic acid intermediate with benzyloxy substituents at the 2- and 6-positions and a boronic acid group at the 3-position. Its primary purchasing relevance is its potential use as a coupling building block, especially in synthetic routes where a functionalized pyridine ring must be introduced into a larger molecule. Because commercial specifications can vary by supplier and batch, I recommend confirming identity, assay, water content, residual solvents, analytical data, packaging, and delivery terms before placing an order.
This guide is intended for procurement teams, process chemists, medicinal chemists, research laboratories, contract development organizations, and distributors sourcing specialty organic boronic acids. It is also useful when a project has moved beyond small-scale discovery and requires a documented supply plan. I focus on practical evaluation rather than presenting unverified performance claims or assuming that every buyer needs the same grade.
The compound may be relevant to users developing heteroaryl intermediates, screening Suzuki-type cross-coupling reactions, or preparing protected pyridine derivatives for further functionalization. The correct buying decision depends on the intended reaction, scale, required documentation, and acceptable delivery risk. A supplier should therefore be evaluated on both chemical information and commercial execution.
2,6-Bis(benzyloxy)pyridine-3-boronic acid combines three important structural features: a pyridine ring, two benzyloxy substituents, and a boronic acid functionality. The boronic acid group is commonly used as a reactive handle in carbon–carbon bond-forming chemistry, while the benzyloxy groups can serve as protected oxygen-containing substituents within a planned synthetic sequence. The exact behavior in a reaction depends on the catalyst, base, solvent, temperature, concentration, and substrate combination.
In practical terms, this is not simply a commodity solvent or general-purpose reagent. It is a structure-specific intermediate whose value depends on route fit and analytical confidence. I recommend treating the CAS number as the starting point for identification, then checking the chemical name, structure representation, molecular formula, molecular weight, lot number, and analytical package against the material offered.
CAS 2096339-92-1 is a chemical identifier used to distinguish this named substance from other pyridine boronic acids and protected heteroaryl intermediates. However, a CAS number alone does not establish a specific purity level, storage condition, packaging format, manufacturing route, or current stock position. Those details must be confirmed in the supplier’s quotation and technical documentation.
The most relevant application is usually synthetic research involving the boronic acid functionality. In a suitable Suzuki-type coupling, the boronic acid can be considered as a partner for forming a new carbon–carbon bond with an appropriate halide or related electrophile. Whether the reaction is successful must be established experimentally, because heteroaryl boronic acids may show different stability and reactivity from simple aryl boronic acids.
The product may also be used as an intermediate in medicinal chemistry programs where substitution around a pyridine ring is important. The benzyloxy groups may be retained during an early transformation or removed later, depending on the route design. I would not assume that deprotection, coupling, or downstream isolation will perform identically across projects without supporting experimental data.
For this compound, the most meaningful “options” are generally commercial grade, quantity, packaging, and documentation level rather than different material grades with universally accepted definitions. A research quantity may be sufficient for method screening, while a development project may require a larger lot with a more detailed certificate of analysis. I recommend asking the supplier to state clearly whether the quoted material is from current stock, made to order, or subject to a new production schedule.
| Evaluation area | What I recommend checking |
|---|---|
| Identity | CAS number, chemical name, structure, formula, molecular weight, and lot reference |
| Purity | Assay method, reported purity, related substances, and whether the result is area percent or another basis |
| Physical and analytical data | Appearance, melting behavior if measured, NMR, LC-MS, HPLC, and water or residual-solvent data where applicable |
| Packaging | Container material, net quantity, tamper protection, labeling, and recommended storage statement |
| Supply terms | MOQ, available quantity, lead time, shipping conditions, export documents, and quotation validity |
Do not interpret a missing test as proof of poor quality, but do treat it as a documentation gap that should be resolved before approval. For moisture-sensitive or air-sensitive materials, storage and handling instructions are especially important; the buyer should follow the supplier’s current technical guidance rather than applying a generic assumption.
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Start with the intended reaction and project scale. Specify the target quantity, acceptable purity, required analytical documents, packaging preference, destination country, and whether the material will be used for research, process development, or a regulated workflow. A clear request reduces avoidable quotation revisions.
Ask for a current certificate of analysis or equivalent batch documentation, together with available chromatographic and spectroscopic data. Confirm that the documents correspond to the exact CAS number and lot being offered. If the project depends on a narrow impurity profile, explain that requirement before purchasing rather than after delivery.
Compare more than the unit price. Review MOQ, production lead time, packaging, payment terms, shipping responsibility, export paperwork, and the supplier’s ability to support repeat orders. For early screening, buyers may compare quotations at 1 g, 5 g, and 25 g quantities to understand how price and availability change across common research scales; these are planning quantities, not guaranteed pack sizes.
On receipt, inspect the label, container, seal, quantity, lot number, and accompanying documents. Your laboratory should apply its own incoming-material procedure, which may include identity testing and purity confirmation. Supplier documentation supports qualification, but it should not replace the buyer’s internal quality requirements.
Specialty intermediates are often priced according to synthesis complexity, production scale, raw-material availability, analytical burden, and packaging requirements. A low quoted price may not represent the lowest total cost if the material has a long lead time, limited documentation, or unsuitable packaging. I recommend requesting a written quote that separates product price, handling charges, freight, taxes, and any custom-documentation fees.
Lead time should be treated as a planning variable rather than an absolute promise until the supplier confirms stock and production status. As an internal procurement target, buyers may ask for a written response within 24–72 hours for technical and commercial questions, while recognizing that actual response time depends on the request complexity and time zone. For repeat programs, discuss forecasts and safety stock early, especially when a project cannot tolerate a single-source interruption.
At Maison Chemical, I approach this product as a B2B specialty chemical sourcing requirement rather than a simple catalog transaction. We can discuss the requested quantity, intended use, specification expectations, packaging, destination, and documentation needed for your internal review. Availability, MOQ, lead time, and final commercial terms should be confirmed for each inquiry because they can change with production planning and order requirements.
When you contact Maison Chemical, provide the CAS number 2096339-92-1, target quantity, destination country, desired delivery date, and any required analytical or regulatory documents. If you are comparing multiple suppliers, tell us which specification points are decisive, such as HPLC purity, water content, residual solvents, or a particular packaging format. This allows us to prepare a more relevant quotation and identify information that still requires confirmation.
In answer to the buying question, 2,6-Bis(benzyloxy)pyridine-3-boronic acid CAS 2096339-92-1 should be evaluated as a specialized heteroaryl boronic acid intermediate whose suitability depends on your synthetic route and documentation requirements. The most responsible purchase decision combines structural identity, batch-specific analytical evidence, commercial transparency, and realistic supply planning. I do not recommend selecting solely on catalog name or unit price.
Before requesting a quotation, define your target quantity, application stage, purity expectation, required documents, destination, and delivery schedule. Then contact Maison Chemical for current availability, MOQ, lead time, packaging, and technical support. With these points confirmed in writing, your team can make a more reliable sourcing decision and reduce avoidable delays during synthesis development.
Contact us to discuss your requirements of 2,6-Bis(benzyloxy)pyridine-3-boronic acid CAS 2096339-92-1. Our experienced sales team can help you identify the options that best suit your needs.
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