4-Butylphenylboronic Acid CAS 145240-28-4 Supplier and Buying Guide

4-Butylphenylboronic acid, CAS 145240-28-4, is an aryl boronic acid used primarily as a synthetic building block in palladium-catalyzed cross-coupling and related organic chemistry research. Its molecular formula is commonly represented as C₁₀H₁₅BO₂, with a calculated molecular weight of approximately 178.04 g/mol. At Maison Chemical, I help buyers evaluate identity, purity, documentation, packaging, and supply conditions before placing an order.

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The right supplier is not selected by price alone. Buyers should confirm the exact chemical identity, required assay, analytical documentation, packaging format, shipping conditions, and whether the material is intended for laboratory, process-development, or manufacturing use. Because specifications and availability can vary by batch and supplier, I recommend requesting a current specification sheet, certificate of analysis, safety data sheet, and quotation before making a final decision.

Who This Guide Is For

This guide is intended for procurement teams, medicinal chemistry groups, process development laboratories, custom synthesis companies, distributors, and manufacturers sourcing 4-Butylphenylboronic acid for a defined chemical application. It is also useful for buyers comparing research-grade material with larger-volume or project-specific supply options. I focus on practical sourcing decisions rather than treating every supplier specification as interchangeable.

The product may be relevant when a project requires a butyl-substituted aryl boronic acid rather than an unsubstituted phenylboronic acid or another alkyl-substituted analogue. The butyl group can influence the electronic and physical behavior of a reaction intermediate, but the final suitability must be confirmed experimentally in the buyer’s own reaction system. A supplier should therefore provide clear identity and batch information rather than relying only on a catalog name.

Basic Chemical Context

Identity and Molecular Information

The CAS number is the first identity check, but it should not be the only one. I advise buyers to compare the CAS number, molecular formula, molecular weight, structure, and analytical results on the supplier’s documents. This helps reduce the risk of receiving a positional isomer, an incorrectly labeled derivative, or a material that does not match the intended synthetic route.

Types, Grades, and Specification Options

Research and Development Supply

For early-stage research, buyers commonly prioritize verified identity, reliable assay, suitable packaging, and a certificate of analysis. The required quantity may be small, but documentation remains important when the compound will be used in publication, method development, or a regulated project. I recommend requesting a representative batch report instead of assuming that a catalog specification applies uniformly to every lot.

Process Development and Larger-Volume Supply

Process-development buyers usually need more than a product name and nominal purity. They may also evaluate residual solvents, water content, elemental impurities, particle or physical form, batch consistency, and change-control communication. These requirements should be agreed before scale-up because a specification suitable for discovery chemistry may not be sufficient for a manufacturing process.

Specification targets should be project-defined. For example, a buyer may request an assay of at least 98.0%, a defined water limit such as 0.5%, and a pilot quantity of 10–100 g, but these figures are examples for discussion rather than a claim about every available batch. Maison Chemical can review the requested specification and confirm which values are supported by the available batch documentation.

Matching the Product to the Application

Suzuki-Miyaura and Related Cross-Coupling

Aryl boronic acids are widely used as coupling partners in Suzuki-Miyaura chemistry, where the boronic acid component can participate in carbon–carbon bond formation under suitable reaction conditions. Whether 4-Butylphenylboronic acid performs well depends on the reaction partners, catalyst, base, solvent, temperature, atmosphere, and work-up procedure. I therefore present it as a useful building block, not as a guarantee of yield or selectivity.

Medicinal Chemistry and Molecule Discovery

The para-butyl substituent may be selected when a project is exploring hydrophobic substitution patterns or structure–activity relationships. In this context, the compound is generally valued as a defined intermediate that can be incorporated into a larger target structure. Researchers should confirm chemical stability, solubility, and reaction compatibility in their own screening or synthesis workflow.

Custom Synthesis and Intermediate Development

Custom synthesis organizations may use this material as an input for preparing more complex biaryl or substituted aromatic compounds. For these projects, lot traceability and repeat supply can be as important as the initial price. If the route is moving toward scale-up, I recommend discussing projected annual demand and qualification samples early.

A Practical Selection Framework

Step 1: Confirm the Exact Identity

Start with CAS 145240-28-4 and compare the requested structure with the supplier’s product description. Ask whether the quoted material is the free boronic acid or a protected boronate ester, because these are different materials with different handling and reaction requirements. Confirm that the name, formula, molecular weight, and analytical identification are consistent.

Step 2: Define the Required Quality Level

Do not request “high purity” without defining how purity will be evaluated. State the minimum assay, acceptable impurity profile, residual solvent expectations, water limit, and required analytical techniques where relevant. A typical document package may include HPLC or GC data, NMR information, Karl Fischer water data, and a safety data sheet, but the exact package should match the application.

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Step 3: Match Quantity and Packaging

Choose packaging based on the intended use, storage duration, and handling environment. A laboratory buyer may need a small, clearly labeled container, while a process team may require multiple containers or a larger pack with stronger lot-control requirements. Ask the supplier to confirm net weight, container type, labeling, secondary packaging, and whether repacking affects traceability.

Step 4: Review Commercial Terms

Price should be evaluated together with minimum order quantity, sample policy, production status, shipping route, payment terms, and lead time. Lead time is often quoted in business days, but it can change according to stock status, analytical release, packaging, export documentation, and destination requirements. I recommend requesting a written quotation that separates product cost from shipping and any document or handling charges.

Supplier Evaluation Checklist

• Can the supplier confirm CAS 145240-28-4 and the requested molecular structure?
• Is a current certificate of analysis available for the quoted batch?
• Does the specification define assay, impurities, water, and residual solvents where needed?
• Can the supplier provide an SDS and appropriate transport documentation?
• Are packaging, labeling, lot number, and retest or review information clearly stated?
• Can the supplier support both sample evaluation and repeat orders?
• Are the quoted MOQ, lead time, Incoterms, and payment conditions explicit?
• Can the supplier review custom specifications without promising unsupported results?

These questions help distinguish a transactional reseller from a supplier able to support technical procurement. I also encourage buyers to compare actual batch documents rather than comparing only website descriptions. A lower unit price may not be advantageous if the material requires additional testing, arrives in unsuitable packaging, or cannot be supplied consistently.

Pricing, MOQ, and Lead-Time Considerations

The price of 4-Butylphenylboronic acid can vary with quantity, purity requirement, batch availability, packaging, analytical testing, and destination. Small laboratory quantities often carry higher per-gram costs because fixed handling and documentation expenses are distributed over a smaller order. Larger quantities may improve unit economics, but only when the buyer has sufficient demand and appropriate storage controls.

MOQ should be negotiated according to the project stage. For initial evaluation, a sample or small pack may be more practical than committing to a larger quantity, while a validated process may justify a scheduled supply arrangement. Maison Chemical can review the required quantity, target specification, destination, and timing before confirming a commercial offer.

Common Buying Mistakes

Confusing Similar Chemical Names

Buyers sometimes compare 4-Butylphenylboronic acid with butyl-substituted boronate esters or with boronic acids containing different positional isomers. These products may not be direct substitutes. Checking the CAS number and structure before comparing price prevents an avoidable sourcing error.

Assuming Catalog Purity Equals Process Suitability

A stated assay does not automatically describe every impurity relevant to a sensitive reaction or downstream process. If a project has strict requirements, the buyer should specify the analytical method and acceptance limits in the purchase inquiry. This creates a clearer basis for supplier confirmation and batch release.

Ignoring Storage and Handling Documentation

Boronic acids should be handled according to the supplier’s SDS and product-specific recommendations. Buyers should review moisture sensitivity, container closure, temperature guidance, personal protective equipment, and disposal requirements before receiving the material. When storage conditions are uncertain, request written guidance rather than applying a generic assumption.

How Maison Chemical Supports Buyers

At Maison Chemical, I support B2B sourcing by aligning the requested identity and specification with the buyer’s application. Our quotation process can address product name, CAS number, required quantity, target purity, packaging, destination, and document requirements in one inquiry. This approach helps technical and purchasing teams evaluate the same commercial information.

We can also discuss sample evaluation, repeat-order planning, and project-specific documentation when those requirements are defined in advance. Availability, MOQ, lead time, and final pricing are confirmed case by case rather than presented as unsupported fixed promises. Buyers should send their target quantity and specification so I can provide a more relevant response.

Key Takeaways

• 4-Butylphenylboronic acid CAS 145240-28-4 is an aryl boronic acid building block used in synthetic chemistry, including suitable cross-coupling applications.
• Its commonly represented formula is C₁₀H₁₅BO₂, with an approximate molecular weight of 178.04 g/mol.
• Identity, assay, impurity profile, water content, packaging, documentation, MOQ, and lead time should be evaluated together.
• Application suitability must be confirmed in the buyer’s own reaction and process conditions.
• A supplier inquiry should include CAS number, quantity, target specification, destination, and required documents.

Conclusion and Next Steps

The best way to buy 4-Butylphenylboronic acid CAS 145240-28-4 is to treat the purchase as a technical sourcing decision, not simply a catalog comparison. First confirm the exact structure and CAS number, then define the quality and documentation required for your application. Finally, compare suppliers on batch evidence, packaging, commercial terms, communication, and repeat-supply capability.

Maison Chemical is ready to review your inquiry for 4-Butylphenylboronic acid. Please provide the required quantity, target purity or specification, preferred packaging, destination country, and desired delivery schedule. I can then help you assess the appropriate supply option and prepare a quotation based on your actual project requirements.

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