What Is 4-Isopropylbenzeneboronic Acid CAS 16152-51-5? Properties, Uses, and Specifications

4-Isopropylbenzeneboronic acid, also called 4-isopropylphenylboronic acid, is an organoboron compound used mainly as a building block in organic synthesis. Its CAS Registry Number is 16152-51-5, its molecular formula is C₉H₁₃BO₂, and its molar mass is approximately 164.01 g/mol. The molecule contains a phenyl ring bearing an isopropyl group and a boronic acid group in the para position. A common use is as an aryl coupling partner in Suzuki–Miyaura reactions, although suitability depends on the reaction design and the other reagents.

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Key Takeaways

• 4-Isopropylbenzeneboronic acid is an arylboronic acid identified by CAS 16152-51-5.
• Its para-isopropyl substituent and boronic acid functionality make it a potential starting material for carbon–carbon bond formation.
• Theoretical mass conversions based on a molar mass of 164.01 g/mol are 164.0 mg per 1.00 mmol and 1.640 g per 10.00 mmol.
• Appearance, assay, water content, packaging, and storage requirements should be confirmed against the current batch documentation and safety data sheet.

What Is 4-Isopropylbenzeneboronic Acid?

This chemical is an aromatic boronic acid: a benzene ring is bonded to a boronic acid group, while an isopropyl substituent occupies the ring’s 4-position. The para arrangement distinguishes it from other positional isomers, such as ortho- or meta-substituted analogues. Its molecular formula, C₉H₁₃BO₂, describes the atoms in one molecule, while the CAS number helps buyers and laboratories distinguish the substance in product records and purchasing systems.

The compound is generally considered a synthetic intermediate rather than a finished-use product. In research and process chemistry, chemists may evaluate it as a source of the 4-isopropylphenyl group when constructing more complex molecules. The exact application, reaction performance, and handling requirements depend on the intended synthesis and should be established through appropriate technical review.

Identity and Basic Chemical Data

The molar mass is useful for planning quantities, but it does not establish product purity or assay. For theoretical calculations, 1.00 mmol corresponds to approximately 164.0 mg of pure compound, and 10.00 mmol corresponds to approximately 1.640 g. Actual weighing and reaction charges should account for the assay stated on the supplied certificate of analysis, when available.

Core Functions and Uses

The boronic acid group is the main synthetic handle in this molecule. A common role for arylboronic acids is participation in palladium-catalyzed Suzuki–Miyaura cross-coupling, where an aryl group can be coupled with a suitable organic halide or related coupling partner. The specific catalyst, base, solvent, temperature, reaction time, and stoichiometry are selected for the full reaction system; there is no single set of conditions that can be assumed to work for every substrate.

The isopropyl group provides a defined substituent on the aromatic ring and remains part of the aryl fragment when that fragment is incorporated into a product. This can make the compound relevant when a target structure specifically calls for a para-isopropylphenyl unit. It should not be treated as interchangeable with phenylboronic acid or another substituted boronic acid, because changing the substituent changes the identity and properties of the resulting molecule.

Typical Application Scenarios

• Medicinal and discovery chemistry: Researchers may screen the compound as a building block when preparing or modifying aromatic structures. Its use depends on the target design and validated reaction conditions.
• Organic synthesis development: Process and research chemists may assess it in coupling studies that introduce a 4-isopropylphenyl group.
• Specialty chemical development: It may be considered as an intermediate for routes to more complex molecules, subject to project-specific safety, quality, and regulatory assessments.

These are potential synthetic contexts, not guarantees of reaction yield or suitability. Buyers should share the intended application and relevant technical requirements when requesting product information, particularly if the material will be used beyond exploratory laboratory work.

Properties and Specification Considerations

Core identity data can be stated from the molecular structure, but many purchasing specifications are batch-dependent. Appearance, assay, water content, impurity profile, and residual solvent information should be verified using the current product specification and batch documentation rather than inferred from the chemical name. If a particular test method or acceptance limit is necessary, buyers should define it before ordering.

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What to Confirm in a Product Specification

Do not assume a particular melting point, solubility, shelf life, or storage temperature without a reliable product-specific document. Conditions can vary by grade, batch, packaging, or supplier guidance. For safe use, consult the safety data sheet and site procedures before opening or handling the material.

How to Select the Right Grade and Supplier

Start with the role the compound will play in your process. A small-scale route-screening study may have different documentation and quantity needs from a scale-up campaign or a controlled manufacturing process. Clarifying the application helps align the requested assay, impurity controls, packaging, and documentation with the actual acceptance criteria.

Buyer Selection Checklist

1. Confirm chemical identity: Match the product name and CAS 16152-51-5 to your internal specification.
2. Set measurable quality requirements: Define assay, impurity, water, or other limits only where your process requires them.
3. Check documentation: Ask which documents are supplied for the offered lot, such as a certificate of analysis and safety data sheet.
4. Align quantity and packaging: Request a quotation for the needed quantity and confirm available pack options rather than assuming stock or a minimum order quantity.
5. Discuss delivery requirements: Share the destination, target schedule, and any import or handling constraints so the supplier can assess feasibility.

Supplier evaluation should focus on clear product identification, transparent batch documentation, communication about specification limits, and a practical response to logistics questions. If your organization requires a specific test method, audit documentation, or change-control information, raise that requirement during quotation rather than after order confirmation. These checks help reduce avoidable differences between a requested material and the material your team is prepared to receive.

Supplier Support from Maison Chemical

Maison Chemical supplies chemicals for B2B buyers and can discuss 4-Isopropylbenzeneboronic acid CAS 16152-51-5 against your project requirements. For a useful quotation, provide the requested quantity, destination, target delivery window, and any required assay or documentation criteria. We can then confirm the applicable product information and commercial details for the offer.

Because availability, packaging, and batch specifications can change, buyers should verify current details before placing an order. Maison Chemical does not recommend treating general chemical identity data as a substitute for lot-specific documents or a formal product specification. For regulated or process-critical use, review the supplied documentation with your quality, safety, and technical teams.

Conclusion: Is This the Right Boronic Acid for Your Project?

4-Isopropylbenzeneboronic acid is an arylboronic acid with CAS 16152-51-5, formula C₉H₁₃BO₂, and a molar mass of approximately 164.01 g/mol. Its principal value is as a potential synthetic building block for introducing a para-isopropylphenyl group, including in suitable Suzuki–Miyaura coupling routes. Whether it is appropriate for a specific synthesis depends on the target structure, reaction conditions, and required material quality.

As a next step, compare the identity data with your route specification, define the quality and documentation requirements, and request current batch and quotation details. Contact Maison Chemical with your quantity, destination, and technical criteria to discuss sourcing options. This approach gives your team a clear basis for evaluating the compound before purchase.

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