4-Methoxyphenylboronic Acid CAS 5720-07-0: Properties, Applications, and Sourcing Guide

4-Methoxyphenylboronic acid, also called 4-methoxybenzeneboronic acid or p-anisylboronic acid, is an aromatic boronic acid used mainly as a building block in carbon–carbon bond-forming synthesis. Its CAS number is 5720-07-0, its molecular formula is C₇H₉BO₃, and its molecular weight is 151.96 g/mol. Buyers evaluating it should confirm the required assay, analytical documentation, packaging, and delivery terms for their specific project rather than relying on a generic product description. This guide explains the compound’s role, selection considerations, and practical steps for requesting a supply quotation from Maison Chemical.

Read more

Key Takeaways

• 4-Methoxyphenylboronic acid is an arylboronic acid commonly selected as a coupling partner in Suzuki–Miyaura chemistry.
• Its methoxy-substituted phenyl group can be incorporated into more complex organic molecules, subject to reaction design and substrate compatibility.
• For procurement, compare the specification and supporting documents, not just the product name or quoted price.
• Ask Maison Chemical to confirm current availability, MOQ, lead time, packaging, and documentation against your order requirements.

Who This Guide Is For

This guide is intended for procurement teams, process chemists, research organizations, and chemical distributors assessing 4-Methoxyphenylboronic acid for laboratory or manufacturing use. It is useful when you need to confirm product identity, determine whether the compound fits a synthetic route, or prepare a supplier inquiry. It does not replace a project-specific risk assessment or a review of the supplier’s current batch documents. If your application has defined impurity limits or regulatory requirements, include them when requesting a quotation.

Basic Concept and Chemical Context

Identity and Structure

The molecule contains a phenyl ring bearing a methoxy group in the para position and a boronic acid group attached to the ring. This combination makes it an arylboronic acid reagent: the aryl group is the portion commonly transferred in suitable cross-coupling reactions. The methoxy substituent is part of the product’s structure and may influence reactivity and the properties of the resulting compound. Confirm the identity using the stated name and CAS number together, especially when comparing catalog listings or purchase specifications.

Physical and Handling Information

Product literature commonly describes 4-Methoxyphenylboronic acid as a solid, but appearance and other batch-specific details should be confirmed against the supplier’s specification. Some reference and commercial listings report a melting range around 208–212 °C; values and test methods can differ, so treat this as an identification reference rather than a release criterion. The melting range is not a substitute for assay, impurity, or identity testing. Request the current certificate of analysis (COA) and safety data sheet (SDS) for the offered batch before purchase.

Applications and Application Matching

Suzuki–Miyaura Cross-Coupling

A principal use for this compound is as an arylboronic acid partner in Suzuki–Miyaura cross-coupling with an appropriate organic halide or related coupling partner. The reaction can provide access to methoxy-substituted biaryl and other aryl-containing structures, depending on the substrates, catalyst system, and conditions selected. This makes the compound relevant to building-block synthesis and route development in research and process chemistry. It is not suitable for every coupling: substrate reactivity, functional-group tolerance, and reaction conditions require evaluation.

Intermediate and Library Synthesis

The para-methoxyphenyl unit can also be useful when preparing intermediates or sets of related compounds for further chemical development. In these cases, buyers should check whether the methoxy group is intended to remain in the final structure or serve as a functional feature for later transformations. A route may require a particular impurity profile or trace-metal control, especially if the material will enter a sensitive downstream step. Discuss those limits with the supplier before placing an order rather than assuming a general-purpose grade will meet them.

Product Options and Key Specifications

This is a defined chemical identity rather than a family of interchangeable boronic acids. Commercial offerings may differ in assay, impurity profile, packaging configuration, and the documentation supplied, so review the actual specification for each offer. Do not infer a grade, particle size, or guaranteed purity from the compound name alone. Where a specific test method or limit matters, state it in the inquiry and ask whether it can be supported.

Maison Chemical Product Page

Buyer Selection Framework

1. Define the Technical Requirement

Start with the intended use and scale, then specify the required assay, impurity limits, and any handling or analytical requirements. If the material is for route screening, your needs may differ from those for a validated or scaled process. Provide a target quantity and preferred delivery window so the supplier can assess the request accurately. If your organization uses an approved specification format, attach it or summarize its critical limits.

2. Review Evidence Before Comparing Offers

Compare suppliers using batch-specific documentation where available, and check that the product identity matches CAS 5720-07-0. Confirm whether the quoted price applies to the requested quantity and whether packaging, documentation, and transport are included or quoted separately. A low headline price may not represent the lowest total procurement cost if the offered pack size or lead time does not fit your project. Ask for clarification on any specification that is absent or ambiguous.

3. Screen the Material in the Intended Route

For reaction development, use your established laboratory procedures and assess conversion, selectivity, and impurity formation with the actual substrates. As an experimental planning example—not a universal recipe—chemists may screen substrate concentrations such as 0.1–0.5 mol/L, then adjust based on solubility, mixing, and reaction performance. Catalyst, base, solvent, temperature, and stoichiometry must be selected for the particular reaction. Scale-up should follow appropriate process-safety and technical review.

Pricing, MOQ, and Lead Time

The price for 4-Methoxyphenylboronic acid can depend on order quantity, requested specification, packaging, documentation, and shipping destination. MOQ and lead time are offer-specific and should be confirmed directly rather than assumed from another listing or an earlier purchase. For a useful quotation, provide the required quantity, destination, target delivery date, and any quality or document requirements. If the order is for evaluation followed by potential scale-up, state both the initial amount and the possible follow-on demand.

Supplier Evaluation Checklist

• Does the quotation identify the product as 4-Methoxyphenylboronic acid, CAS 5720-07-0?
• Can the supplier provide the relevant batch specification, COA, and SDS for review?
• Are assay basis, test methods, packaging, MOQ, and lead time clearly stated?
• Can the supplier address your required impurity limits or documentation needs, subject to confirmation?
• Are shipping terms and any special handling requirements clear for your destination?

Maison Chemical supplies organic chemical products and can review inquiries for 4-Methoxyphenylboronic acid against a buyer’s requested quantity and specification. Availability, packaging, lead time, and supporting documents should be confirmed for each order. Sharing your technical requirements at the inquiry stage helps the team assess whether the offered material aligns with your purchasing and application needs. No batch should be treated as meeting a project-specific requirement until the relevant documents have been reviewed.

Conclusion and Next Steps

4-Methoxyphenylboronic acid (CAS 5720-07-0) is a methoxy-substituted arylboronic acid used principally as a synthetic coupling building block. Its suitability depends on the reaction and the specification required, so buyers should verify identity, assay, impurity expectations, and batch documentation before ordering. To move forward, send Maison Chemical your target quantity, destination, desired specification, and delivery timing. The supplier can then confirm the applicable availability, MOQ, lead time, and quotation details for your inquiry.